Our mission
Our mission

Bring native bispecific therapeutics to patients

Our antibody development roots go deep

CD47 targeting
CD47 targeting

Safe and selective blockade of CD47 on tumors

Safe and selective blockade of CD47 on tumors

CD28 targeting

Safe and selective CD28 co-stimulation

Safe and selective blockade of CD47 on tumors

Who we are
Who we are

Our antibody development roots go deep

Our antibody development roots go deep

Our technology
Our technology, natural bispecific antibodies

Multispecific yet natural

κλ bodies

Looking into the future
Looking into the future

Beyond bispecific antibodies

Beyond bispecific antibodies

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  • CD28 targeting
  • How it works
Research collaboration with LamKap Bio

Research collaboration with LamKap Bio


Milestones achieved under research collaboration with LamKap Bio.

Light Chain Bioscience announced that it has achieved two milestones and received corresponding payments under its research and collaboration agreement with the LamKap Bio Group, Pfäffikon, Switzerland.

The collaboration aims at developing bispecific antibodies capable of re-targeting T cells to tumor cells as well as blocking the immune checkpoint CD47 on the same tumors for the treatment of solid cancers. These milestones were achieved upon the successful completion of the discovery phase and designation by LamKap Bio of bispecific antibodies as clinical development candidates with approval to advance to IND-enabling studies and GMP manufacturing with its partner Lonza, Basel, Switzerland.

It is very satisfying to have reached these first important milestones. This is the result of a truly collaborative effort. The successful identification of therapeutic bispecific antibody candidates harnessing different modes of action to kill tumor cells further validates our κλ body platform” said Nicolas Fischer, Light Chain Bioscience’s Chief Executive Officer. “We believe that the native human structure of these bispecific candidates represents a significant advantage for the treatment of patients.”

GENEVA, Switzerland, September 21st 2020

First Patient dosed with NILK-2401 in Phase I clinical trial

First-in-human trial of NILK-2401, a CEACAM5xCD47 bispecific κλ body


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