κλ bodies, truly human
Native, non-engineered, human bispecific antibodies maintain human antibody sequence and structure.
A κλ body consists of:
- 2 identical heavy chains
- 2 different light chains: one kappa (κ) and one lambda (λ)
κλ body discovery, a simple process
We first identify antibodies using our common heavy chain antibody libraries. Then, we simply co-express one heavy chain and the two light chains. The bispecific κλ bodies can be directly tested using the cell culture supernatant or easily purified using standard affinity chromatography.
